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Try out PMC Labs and tell us what you think. Learn More. Data is contained within the article or supplementary material. Arthritis is a widespread inflammatory disease associated with progressive articular surface degradation, ongoing pain, and hyperalgesia causing the development of functional limitations and disability. TRPV1 channel is one of the high-potential targets for the treatment of inflammatory diseases.
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Try out PMC Labs and tell us what you think. Learn More. Duchenne muscular dystrophy DMD is a devastating disease characterized by dystrophin deficiency with subsequent chronic inflammation, myofiber necrosis, and impaired regeneration. Recently, an orally active ApN receptor agonist, AdipoRon, has been identified.
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